Browsing This

Reconcilable Differences: Materials and Methods

Published in Asthma

Patient Recruitment and Study Sample
We performed a cross-sectional study of a sample of 202 English-speaking asthmatic patients between 19 years and 50 years of age residing in the Greater Vancouver Regional District of British Columbia (BC), Canada. One hundred nine subjects were recruited from a random sample of SA P-agonist users identified using the BC Ministry of Health Pharmacare database. Researchers were blinded to the identity of the every patient until the patient consented to participate, thereby protecting each patient’s privacy and ensuring confidentiality. Pharmacare is the pharmaceutical reimbursement program of BC, which provides comprehensive first-dollar coverage for all BC residents on social assistance (plan C), and the general population < 65 years of age (plan E) whose annual family pharmaceutical expenditure exceeds $800 per year. Ninety-three subjects were recruited through media advertising. A detailed description and evaluation of the recruiting method has been published elsewhere. Each subject was assessed in a pulmonary research clinic by trained personnel, and received $25 to defray travel expenses. The institutional and university ethics review boards approved the study protocol, and informed consent was obtained from each participant. buy wellbutrin online

Data Collection
Pulmonary function was measured in accordance with American Thoracic Society criteria. FEV1 was expressed as a percentage of the value predicted based on the patient’s gender, age, and height. All other data were collected by self-report. To control for differences in potency, strength, and formulation, the amount of each specific SA P-agonist used was standardized to the number of canisters of salbutamol metered-dose inhaler (100 Mg/puff, 200 puffs per canister), and each dosage form of ICS was standardized to the equivalent dose of beclomethasone dipropionate by metered-dose inhaler. This dosage standardization methodology has been applied previously.