Tags
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure: Conclusion
This muscle fiber atrophy is associated with significant reductions in tissue force generation, thus limiting resting tonality and potentially contributing the upward crescent shape of the diaphragm. Another potential contributor to the increased diaphragm volume includes ascites. Mutoh and col-leagues have shown, using a piglet model, a 40% reduction in TLC as a result of […]
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure: Discussion
These authors also suggest that, due to the increase in cardiac size, diffusion capacity of the lung suffers adversely, primarily as a consequence of a reduction in membrane diffusion as opposed to pulmonary capillary blood volume. Although moderate but significant correlations were observed between the cardiothoracic index and various components of pulmonary function, these findings […]
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure: Results
The relationship between NYHA class and absolute lung volume and percentage of TTCV that is taken up by the lung is shown in Figure 3, top, A, and bottom, B, respectively. These data suggest a clear relationship between increasing NYHA class and elevated cardiac volume and reduction in lung volume. Figure 4 demonstrates the close […]
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure: Statistical Analysis
Statistical analysis and graphic presentation were accomplished using statistical software (Prism version 4.0; Graphpad; San Diego, CA). One-way analysis of variance was used to test for differences in means among the groups, and unpaired t test was used to compare the means of the participant characteristics and radiographic variables between the control and chronic heart […]
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure: Population Characteristics
The TTC volume (TTCV) was determined as follows: (1) the posteroanterior and lateral view-digitized tracings were divided vertically into five sections, with the upper two sections equally divided into 2.75-cm segments, and the third and fourth sections equally divided between the most superior border of the diaphragm and lower border of the second section; (2) […]
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure: Population Characteristics
This retrospective analysis utilized data from 44 chronic heart failure patients from the database of the Mayo Clinic Heart Failure Service or the Cardiovascular Health Clinic (a preventive and rehabilitative center) from 2000 to 2004 (Table 1). Inclusion criteria included patients with a history of ischemic or dilated cardiomyopathy, stable heart failure symptoms (> 3 […]
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure
Chronic heart failure is a progressive disease resulting in severe morbidity and mortality. Interestingly, certain resting measures of cardiac function (ie, ejection fraction [EF]) correlate poorly with exercise tolerance, and thus it is clear that chronic heart failure becomes a systemic disorder, influencing a number of organ systems that may contribute to activity intolerance. Because […]