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Synchronized Intermittent Mandatory Ventilation With and Without Pressure Support Ventilation in Weaning Patients With COPD From Mechanical Ventilation: Appendix
This additional burden is not negligible: Katz and coworkers have shown that the respirator (Puritan Benett 7200) induces an additional inspiratory work ranging from 10 to 40 percent. Fiastro and coworkers predicted that a 1-mm decrease in the tube diameter results in a 67 to 100 percent increase in this work. Nevertheless, low PSV level […]
Synchronized Intermittent Mandatory Ventilation With and Without Pressure Support Ventilation in Weaning Patients With COPD From Mechanical Ventilation: Conclusion
Our study reassessed in patients with COPD the previously described effects of PSV on the breathing pattern. For PSV levels >12 cm H2O, group 1 patients exhibited significant lower sVe and Sf with higher sVt than did group 2 patients. However, despite this difference in sVe, there was no difference in blood gas values between […]
Synchronized Intermittent Mandatory Ventilation With and Without Pressure Support Ventilation in Weaning Patients With COPD From Mechanical Ventilation: Comment
Respiratory acidosis alone, even without clinical signs of respiratory muscle fatigue, was enough to return to the previous step. With PSV, the average weaning time showed a tendency to be shorter, but the difference between the two groups did not reach the significance level, which is not surprising given the small number of patients studied. […]
Synchronized Intermittent Mandatory Ventilation With and Without Pressure Support Ventilation in Weaning Patients With COPD From Mechanical Ventilation: Discussion
At the end of this study, all patients with COPD were extubated as they had undergone long periods of SB without clinical or/and blood gas value deterioration. The duration of the weaning period appeared lower in group 1 than in group 2: 4.2 ±0.8 days (SIMV/PSV) vs 5.3±1.0 days (SIMV), but the difference did not […]
Synchronized Intermittent Mandatory Ventilation With and Without Pressure Support Ventilation in Weaning Patients With COPD From Mechanical Ventilation: Results
Ten patients were randomized to receive SIMV/ PSV (group 1) and nine were randomized to receive SIMV alone (group 2). The clinical and physical characteristics of the 19 studied patients are given in Table 1. Group 1 and group 2 patients were all cigarette smokers with obstructive lung disease documented by their pulmonary function test […]
Synchronized Intermittent Mandatory Ventilation With and Without Pressure Support Ventilation in Weaning Patients With COPD From Mechanical Ventilation: Measurements
At each step of SIMV rate (te, at each 2 cycles/min decrease), several measurements were performed when a ventilatory steady state was achieved on semirecumbent position: average systolic blood pressure (SBP) and heart rate (HR) from repeated measurements, spontaneous tidal volume (sVt), total and spontaneous minute ventilation (Ve and sVe). The steady state was arbitrarily […]
Synchronized Intermittent Mandatory Ventilation With and Without Pressure Support Ventilation in Weaning Patients With COPD From Mechanical Ventilation: Patients
This prospective study was designed for male COPD patients, intubated and mechanically ventilated because of an acute exacerbation of their disease. All patients exhibited clinically a chronic bronchitis defined as a productive cough with sputum production for 3 months per year for a 2-consecutive-year period (American Lung Association criteria and an irreversible chronic airflow limitation […]