Vasoactive intestinal polypeptide and phentolamine
Vasoactive intestinal polypeptide (VIP) is a postganglionic neurotransmitter which seems to have a role in the erectile process. VIP is described as a ‘facilitator’ of erections because intracavernosal injection leads to tumescence only. A combination of VIP and phentolamine can be very effective. In a study of 52 men with erectile [...]

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Effectiveness
There are a multitude of publications on the use of PGEl. One large multicentre trial of 187 patients with erectile dysfunction reported good or very good patient satisfaction in 91% of patients. In a study by Stackl of 550 sufferers, 70% reported a full erection lasting for more than 30 minutes and all were adequate [...]

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