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Difficult-to-treat ED
In the two trials mentioned in the previous section, the patient population was largely a primary care population of relatively healthy men with ED of varying severities and etiologies. To the contrary, a multicentered, randomized, double-blind, placebo controlled trial evaluated how tadalafil 20 mg improved ED in men presenting to tertiary care centers with more [...]
The general ED population
The most frequently referenced study supporting the efficacy of tadalafil is an integrated analysis of 5 randomized, double-blind, placebo controlled, multicentered phase III trials from 1112 men at 74 centers worldwide. The average age was 59, and the etiology of ED was 61% organic, 9% psychogenic, and 31% mixed. The ED severity at baseline was [...]
External vacuum devices
For patients with erectile dysfunction who cannot tolerate or do not respond to intracavernosal injections, there is a choice between a penile prosthesis or a vacuum device. A vacuum device works by creating penile congestion and enough rigidity to allow penetration (figure l). There are no comparative controlled studies and most of the questionnaire reviews [...]
PROSTAGLANDIN El (PGEl)
Effectiveness
There are a multitude of publications on the use of PGEl. One large multicentre trial of 187 patients with erectile dysfunction reported good or very good patient satisfaction in 91% of patients. In a study by Stackl of 550 sufferers, 70% reported a full erection lasting for more than 30 minutes and all were adequate [...]
Medical treatment of erectile dysfunction
There has been a tremendous increase in demand for the treatment of erectile dysfunction in the last 10 years. This has occurred partly because of a greater understanding and awareness by both the general public and clinicians, and also because there now exists a range of effective treatments. The choice of treatments is increasing rapidly [...]
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What causes ED (Erectile Dysfunction)?
Erectile Dysfunction (ED) is the inability to get and maintain an erection of the penis for satisfactory sexual intercourse. In most cases, ED is a physical health problem, as opposed to psychological. It is usually caused by or associated with high blood pressure, high cholesterol, or diabetes, problems that are more often present as we [...]
