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Reconcilable Differences: Conclusions

Posted in March 17th, 2015
Published in Asthma

An assumption of this analysis is that the excessive use of SA P-agonists is synonymous with asthma control, an assumption that is supported by both the metrics of control included in the current asthma management guidelines and the Asthma Control Questionnaire, and expert opinion. These results are also dependent on the measurement and adjustment for […]

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Reconcilable Differences: Asthma control

Posted in March 16th, 2015
Published in Asthma

Connolly et al reported poorer asthma control based on a greater reversibility of airway disease in men in lower social classes. The only studies to assess differential pharmacologic management are two US studies done in children and adolescents, both of which concluded that asthma management may be inadequate in lower social classes. The likelihood that […]

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Reconcilable Differences: Discussion

Posted in March 4th, 2015
Published in Asthma

Although there was no association between age, gender, or genotype and SA P-agonist use, we identified a strong and significant association between SES and the amount of SA P-agonist medications used by asthmatics, independent of asthma severity. This association was consistent across all proximate and contextual measures of SES, with gradients identified in the expected […]

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Reconcilable Differences: SA

Posted in March 3rd, 2015
Published in Asthma

Both annual household income and level of education completed were negatively and significantly associated with the magnitude of SA (3-agonist used, with a consistent gradient across social classes (Fig 2). Adjustment for family size based on the lowincome cutoff did not affect the results. Although the gradient based on education was consistent and the overall […]

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Reconcilable Differences: CLDSI

Posted in March 2nd, 2015
Published in Asthma

This sample was well distributed across all levels of asthma severity (Table 2). All three severity scores were normally distributed across the entire range of the score, with the Ng Score encompassing its entire range, while the CLDSI and ASS ranged from 5 and 6 to 28, respectively. Table 2 also illustrates the construct validity […]

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Reconcilable Differences: Results

Posted in March 1st, 2015
Published in Asthma

The proportional odds assumption was tested for each model using a Score test. If the hypothesis of proportional odds was rejected (p 4 canisters, or 12 canisters) are reported for each association.

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Reconcilable Differences: Statistical Analysis

Posted in February 28th, 2015
Published in Asthma

Three interval score measures of asthma severity, each based on different dimensions of asthma severity, were also used. The asthma symptom sum (ASS) is a summed score of patient-rated severity of wheeze, shortness of breath, cough, and chest tight-ness. The chronic lung disease severity index (CLDSI) is a validated summed score proposed for use in […]

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