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Inspiratory Muscle Training in Patients With Duchenne Muscular Dystrophy: Conclusion

Posted in May 14th, 2014
Published in Pulmonary Function

Although the strength and endurance of the inspiratory muscles improved with training, the pulmonary function parameters, especially VC and 12s-MW, did not change. Similar effects were reported by Chen and coworkers and by Flynn and associates in patients with COPD during respiratory muscle training. Pulmonary function testing is known to be an insensitive parameter of […]

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Inspiratory Muscle Training in Patients With Duchenne Muscular Dystrophy: Discussion

Posted in May 12th, 2014
Published in Pulmonary Function

Our study shows the following results: (1)    In patients with DMD, respiratory muscles and in particular the diaphragm, are trainable in terms of strength and endurance, provided that their ventilatory function is not severely restricted. (2)    In patients with VC values less than 25 percent predicted and/or a PaC02 of more than 45 mm Hg, […]

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Inspiratory Muscle Training in Patients With Duchenne Muscular Dystrophy: Analisys

Posted in May 10th, 2014
Published in Pulmonary Function

At the beginning of the study the Pesmax and Pdimax values were not significantly different in the two groups (Fig 1, Table 2). After the 6-month training period, however, the ten patients who completed the training had significantly higher Pesmax and Pdimax values than the 12 control subjects without severe functional impairment (p < 0.001) […]

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Inspiratory Muscle Training in Patients With Duchenne Muscular Dystrophy: Results

Posted in May 8th, 2014
Published in Pulmonary Function

The mean of the five highest pressure values during ten maximal static inspiratory efforts against the almost occluded airway was used as the minimal pressure value which had to be reached during such efforts at home. This value had to be adjusted each month anew, if the patients could meanwhile achieve higher mean pressure values. […]

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Inspiratory Muscle Training in Patients With Duchenne Muscular Dystrophy: Protocol

Posted in May 6th, 2014
Published in Pulmonary Function

The catheters were perfused with distilled water at a constant flow of 25 ml/h. The proximal ends were coupled to pressure transducers (Could-Statham, P23ID, Cleveland). The catheter-pressure transducer system was described in detail previously. The Pdi was calculated by subtracting esophageal pressure (Pes) from the gastric pressure (Pga) by an electronic subtraction circuit. The Pes, […]

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Inspiratory Muscle Training in Patients With Duchenne Muscular Dystrophy: Inspiratory Muscle Training at Home

Posted in May 4th, 2014
Published in Pulmonary Function

At home, patients had to perform both resistive breathing maneuvers and maximal static inspiratory efforts against the almost occluded resistance. Training was done in the sitting position and a noseclip was used. The inspiratory resistive breathing training consisted of ten loaded breathing cycles of 1-min duration each, with 20-s intervals between them, twice daily. The […]

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Inspiratory Muscle Training in Patients With Duchenne Muscular Dystrophy: Training Apparatus

Posted in May 2nd, 2014
Published in Pulmonary Function

For this study, a special training apparatus was constructed to enable the patient to actually adhere to the prescribed training intensity. In addition, the number of correctly and incorrectly performed exercises was stored by the apparatus to give the physician the possibility to control the training of the patient. The training apparatus enabled the patient […]

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