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Canadian Cialis Effective at ED Treatment

Tags: impotence

Canadian Cialis contains 20 mg tadalafil per tablet. Other ingredients are:

  • lactose monohydrate;
  • croscarmellose sodium;
  • hydroxypropyl cellulose;
  • microcrystalline cellulose;
  • sodium lauryl sulfate;
  • magnesium stearate;
  • colorant mixture – Opadry II;
  • talc.

The Pharmacological Action of Cialis

Cialis is drug for erectile dysfunction treatment. It is a reversible selective inhibitor of specific phosphodiesterase type 5 (PDE5). When sexual stimulation causes local release of nitric oxide, inhibition of PDE5 leads to cGMP levels increase in the cavernous body. The result is relaxation of smooth muscles arteries and blood flow to the penis tissues appear causing erection. Tadalafil has no effect in the absence of sexual stimulation.

Cialis improves erection and possibility of successful sexual intercourse. Canadian Cialis is available in our online store – Canadian Health and Care Mall.

Cialis action lasts for 36 hours. The effect is already apparent after 16 minutes after taking the drug in the presence of sexual excitement.

Canadian Cialis in healthy individuals does not cause significant changes in systolic and diastolic blood pressure compared with placebo in the prone position and standing. Tadalafil does not cause significant heart rate changes. Cialis does not cause changes in color recognition (blue / green), due to its low affinity for PDE6. In addition, effect of Cialis on visual acuity, electroretinogram, intraocular pressure and pupil size are not observed.

Recommended daily dose of Cialis is 10 mg no clinically significant effect on the drug and the number of sperm concentration, motility and morphology of spermatozoa.

satisfaction with Cialis

Indications for Cialis Use

Erectile dysfunction is the main prescription.

The Dosage Regimen of Canadian Cialis

Middle-aged men are encouraged to take Cialis of 20 mg daily. Cialis take at least 16 minutes prior to anticipated sexual activity, regardless of the meal.

Patients can perform attempt to conduct sexual intercourse at any time within 36 hours after dosing in order to set the optimal response time to the drug intake.

The maximum recommended dose frequency is 1 times / day.

For older men special dose adjustment is required. Recommendations for drug intake for middle-aged men are also applicable to elderly patients.

Patients with impaired renal and liver function (creatinine clearance> = 30 ml / min) specific dose adjustment is required.

disppointed couple because of ED

Side effects Caused by Cialis

The most frequently side effects are:

  • headache (11%);
  • dyspepsia (7%).

Side effects are usually mild to moderate in severity, transient and decreases with continued dosing.

Perhaps there are the following side effects:

  • general pain;
  • back pain;
  • myalgia;
  • nasal congestion;
  • flushing.

Rare side effects are:

Contraindications to Cialis Use

  1. Concomitant use of drugs containing any organic nitrates;
  2. Child and adolescence under 18 years;
  3. Established hypersensitivity to tadalafil or other components of this preparation.

Cialis Overdose

With single application healthy volunteers at a dose of 500 mg / day, and patients with erectile dysfunction – repeatedly to 100 mg / day, adverse effects were the same as in drug use at lower doses.

Treatment: conducting standard symptomatic therapy.

ED DrugsOther Drugs Influence Taking in Combination with Cialis

The drug Cialis is mainly metabolized by CYP3A4 enzyme. Selective CYP3A4 inhibitor ketoconazole increased the AUC by 107%, and rifampicin reduces it by 88%. Despite the fact that specific interaction has not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, and inhibitors of CYP3A4, such as itraconazole, and erythromycin, Canadian Cialis increases the activity.

At the same time taking antacid medications (magnesium hydroxide/aluminum hydroxide) and tadalafil reduce the rate of absorption of the latter without changing the AUC.

Order Cialis via Canadian Health and Care Mall to provide yourself with high quality cost-efficient medications. Canadian Cialis will revive your sexual life for fifteen minutes. It is the most important for men to be on the top!