Category

Canadian HealthCare Mall: Results of Relation Between Neurocognitive Impairment, Embolic Load, and Cerebrovascular Reactivity

Published in Reactivity

On-pump CABGHITS

In the on-pump group, the mean number of HITS was 335.1 ± 333.5 (range, 24 to 1,229), whereas in the off-pump group, the mean number of HITS was 144.7 ± 180.4 (range, 5 to 632). This difference was significant (Z = — 2.698; p < 0.01).

Since all patients were monitored bilaterally, we could compare the HITS detection in the left and right MCAs. For the on-pump group, we counted 179 ± 227 HITS (53%) in the left MCA and 156 ± 151 HITS (47%) in the right MCA. This difference was not significant. In off-pump patients, HITS tended to be more numerous on the right MCA (106 ± 149; 73%) compared to the left MCA (39 ± 62; 27%), although this trend failed to reach significance (p = 0.057). After square-root transformation of the HITS count to obtain a normal distribution, a repeated-measures, multivariate analyses of variance with eight different surgical maneuvers of on-pump CABG as within-subjects factor was performed and revealed a main effect of surgical maneuver (F = 8.128, p < 0.01). When the different surgical maneuvers of on-pump CABG were assessed separately with paired t tests, significantly more HITS were detected immediately after aortic cannulation (Table 2). Significantly fewer HITS were found after cross-clamping. When cumulating the percentage of HITS associated with the different stages of the operation, 13.9% of the total number of HITS was explained.

Continue reading this post…