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Influence of p2-Adrenergic Receptor Genotype on Airway Function During Exercise in Healthy Adults: Data Collection

Posted in October 14th, 2014
Published in Pulmonary Function

The next session consisted of a cycle ergometry test similar to the first visit. However, during this second study, classical gas exchange measures were collected and subjects also were instructed to perform maximal expiratory flow volume (MEFV) maneuvers at rest and over the last 30 s of each work level (every 2 min). Since most […]

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Influence of p2-Adrenergic Receptor Genotype on Airway Function During Exercise in Healthy Adults: Materials and Methods

Posted in October 13th, 2014
Published in Pulmonary Function

These differences were not observed in children, suggesting the Arg16Gly polymorphism may influence the rate of decline in lung function with aging. The focus of the present study was to determine if common polymorphisms of the (P2AR differentially influence airway tone during and after short-term exercise in healthy subjects without asthma. We hypothesized that subjects […]

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Influence of p2-Adrenergic Receptor Genotype on Airway Function During Exercise in Healthy Adults

Posted in October 12th, 2014
Published in Pulmonary Function

The respiratory system adapts to changes in metabolic demand in an attempt to maintain gas exchange homeostasis at minimal cost. Among the many respiratory adaptations that occur during exercise is exercise-induced bronchodilation, the mechanism of which remains controversial.’2 Changes in airway tone with exercise, although small, are important, as it allows for a large increase […]

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