Author Page
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure: Population Characteristics
The TTC volume (TTCV) was determined as follows: (1) the posteroanterior and lateral view-digitized tracings were divided vertically into five sections, with the upper two sections equally divided into 2.75-cm segments, and the third and fourth sections equally divided between the most superior border of the diaphragm and lower border of the second section; (2) […]
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure: Population Characteristics
This retrospective analysis utilized data from 44 chronic heart failure patients from the database of the Mayo Clinic Heart Failure Service or the Cardiovascular Health Clinic (a preventive and rehabilitative center) from 2000 to 2004 (Table 1). Inclusion criteria included patients with a history of ischemic or dilated cardiomyopathy, stable heart failure symptoms (> 3 […]
Competition for Intrathoracic Space Reduces Lung Capacity in Patients With Chronic Heart Failure
Chronic heart failure is a progressive disease resulting in severe morbidity and mortality. Interestingly, certain resting measures of cardiac function (ie, ejection fraction [EF]) correlate poorly with exercise tolerance, and thus it is clear that chronic heart failure becomes a systemic disorder, influencing a number of organ systems that may contribute to activity intolerance. Because […]
Side Effects With Inhaled Corticosteroids: Conclusion
How often do you monitor for (1) systemic or (2) local adverse events? When asked to rate the overall safety of ICS on a scale of 1 (very safe) to 6 (dangerous), 25% of participants in this meeting rated ICS as very safe, most (40%) chose 2 on the scale, and 35% chose 3 or […]
Side Effects With Inhaled Corticosteroids: Physician Perception of Side Effects With ICS Therapy
A survey of 429 US family physicians and pediatricians in managed-care organizations was conducted by the Pediatric Asthma Care Patient Outcomes Research Team. This survey focused on physicians’ concerns and perceptions. Although 26% of responders thought ICS were very safe and 66% thought they were safe, 47% were at least moderately concerned regarding one or […]
Side Effects With Inhaled Corticosteroids: Systemic Side Effects
The only specific recommendation for monitoring systemic side effects made in the NAEPP 1997 guidelines was to monitor growth in children. However, based on the evidence available at the time, the guidelines recommended the following measures for minimizing potential systemic side effects with ICS: Here • Use a spacer device and rinse the mouth after […]
Side Effects With Inhaled Corticosteroids: Control and Monitoring of Side Effects Local Side Effects
The only other systemic side effect with ICS mentioned in the NAEPP 1997 guidelines was disseminated varicella infection. While oral corticosteroid use, with or without immunosuppression, has been associated with a high risk of severe varicella infection compared with case-matched control sub-jects, no causal relationship has been shown with ICS, despite sporadic case reports of […]