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Reconcilable Differences: Asthma Severity
Both individual (proximate) and population (contextual) measures of SES were used. Proximate measures were based on self-reported annual household income ($20,000, $20,000 to $50,000, and >$50,000, expressed in Canadian dollars), education (years of postsecondary education and highest level completed), and the receipt of social assistance. Exploratory analysis accounting for family size based on the low-income […]
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Reconcilable Differences: Materials and Methods
Patient Recruitment and Study Sample We performed a cross-sectional study of a sample of 202 English-speaking asthmatic patients between 19 years and 50 years of age residing in the Greater Vancouver Regional District of British Columbia (BC), Canada. One hundred nine subjects were recruited from a random sample of SA P-agonist users identified using the […]
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Reconcilable Differences
An association between the excessive use of short-acting (SA) P-agonists and greater asthma-related morbidity and mortality has been identified, raising concerns over their safety. Specifically, asthmatic patients receiving excessive amounts of SA P-agonist experience more frequent emergency department visits, have a greater likelihood of a hospital admission and are at greater risk of having a […]
Side Effects With Inhaled Corticosteroids: Conclusion
How often do you monitor for (1) systemic or (2) local adverse events? When asked to rate the overall safety of ICS on a scale of 1 (very safe) to 6 (dangerous), 25% of participants in this meeting rated ICS as very safe, most (40%) chose 2 on the scale, and 35% chose 3 or […]
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Side Effects With Inhaled Corticosteroids: Physician Perception of Side Effects With ICS Therapy
A survey of 429 US family physicians and pediatricians in managed-care organizations was conducted by the Pediatric Asthma Care Patient Outcomes Research Team. This survey focused on physicians’ concerns and perceptions. Although 26% of responders thought ICS were very safe and 66% thought they were safe, 47% were at least moderately concerned regarding one or […]
Side Effects With Inhaled Corticosteroids: Systemic Side Effects
The only specific recommendation for monitoring systemic side effects made in the NAEPP 1997 guidelines was to monitor growth in children. However, based on the evidence available at the time, the guidelines recommended the following measures for minimizing potential systemic side effects with ICS: Here • Use a spacer device and rinse the mouth after […]
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Side Effects With Inhaled Corticosteroids: Control and Monitoring of Side Effects Local Side Effects
The only other systemic side effect with ICS mentioned in the NAEPP 1997 guidelines was disseminated varicella infection. While oral corticosteroid use, with or without immunosuppression, has been associated with a high risk of severe varicella infection compared with case-matched control sub-jects, no causal relationship has been shown with ICS, despite sporadic case reports of […]