As with every PDE5 inhibitor, tadalafil is absolutely contraindicated with nitrate medications for angina pectoris secondary to the potentiated hypotensive effect the drugs can have together. Because of the longer half-life, treatment with nitrate medications must be deferred for at least 48 hours after ingestion of tadalafil, compared with 24 hours for sildenafil (Viagra) and [...]

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Inform your healthcare provider, during either a physical or online consultation, about all prescription and non-prescription medications you use, especially any nitrate medications (e.g., nitroglycerin, isosorbide dinitrate), nitroprusside (any “nitric oxide donor” medicines), cimetidine, erythromycin, azole antifungals (e.g., itraconazole, ketoconazole pills), mibefradil, rifamycins (e.g., rifampin), high blood pressure medicines, alpha-blockers, or HIV protease inhibitors. Do [...]

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